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Effect of dC → d(m(5)C) Substitutions on the Folding of Intramolecular Triplexes with Mixed TAT and C(+)GC Base Triplets
Oligonucleotide-directed triple helix formation has been recognized as a potential tool for targeting genes with high specificity. Cystosine methylation in the 5′ position is both ubiquitous and a stable regulatory modification, which could potentially stabilize triple helix formation. In this work,...
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| Publicado no: | Biochimie |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811340/ https://ncbi.nlm.nih.gov/pubmed/29277568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2017.12.008 |
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