Midlife Adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation

Understanding how midlife risk factors influence age-at-onset (AAO) of Alzheimer’s disease (AD) may provide clues to delay disease expression. Although midlife adiposity predicts increased incidence of AD, it is unclear whether it affects AAO and severity of Alzheimer’s neuropathology. Using a prosp...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Chuang, Yi-Fang, An, Yang, Bilgel, Murat, Wong, Dean F., Troncoso, Juan C., O’Brien, Richard J., Breitner, JC, Ferruci, Luigi, Resnick, Susan M., Thambisetty, Madhav
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811225/
https://ncbi.nlm.nih.gov/pubmed/26324099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.129
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