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KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring

Kinesin super family protein 2A (KIF2A), an ATP-dependent microtubule (MT) destabilizer, regulates cell migration, axon elongation, and pruning in the developing nervous system. KIF2A mutations have recently been identified in patients with malformed cortical development. However, postnatal KIF2A is...

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Foilsithe in:eLife
Main Authors: Homma, Noriko, Zhou, Ruyun, Naseer, Muhammad Imran, Chaudhary, Adeel G, Al-Qahtani, Mohammed H, Hirokawa, Nobutaka
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811213/
https://ncbi.nlm.nih.gov/pubmed/29313800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30935
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