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Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells

Human SEMAPHORIN 5A (SEMA5A) is an autism susceptibility gene; however, its function in brain development is unknown. In this study, we show that mouse Sema5A negatively regulates synaptogenesis in early, developmentally born, hippocampal dentate granule cells (GCs). Sema5A is strongly expressed by...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Duan, Yuntao, Wang, Shih-Hsiu, Song, Juan, Mironova, Yevgeniya, Ming, Guo-li, Kolodkin, Alex L, Giger, Roman J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236683/
https://ncbi.nlm.nih.gov/pubmed/25313870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04390
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