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Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells

Human SEMAPHORIN 5A (SEMA5A) is an autism susceptibility gene; however, its function in brain development is unknown. In this study, we show that mouse Sema5A negatively regulates synaptogenesis in early, developmentally born, hippocampal dentate granule cells (GCs). Sema5A is strongly expressed by...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Duan, Yuntao, Wang, Shih-Hsiu, Song, Juan, Mironova, Yevgeniya, Ming, Guo-li, Kolodkin, Alex L, Giger, Roman J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236683/
https://ncbi.nlm.nih.gov/pubmed/25313870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04390
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