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A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila

Germline stem cell (GSC) self-renewal and differentiation into gametes is regulated by both intrinsic factors in the germ line as well as extrinsic factors from the surrounding somatic niche. dWnt4, in the escort cells of the adult somatic niche promotes GSC differentiation using the canonical β-cat...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Upadhyay, Maitreyi, Kuna, Michael, Tudor, Sara, Martino Cortez, Yesenia, Rangan, Prashanth
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811049/
https://ncbi.nlm.nih.gov/pubmed/29370168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007154
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