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A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila

Germline stem cell (GSC) self-renewal and differentiation into gametes is regulated by both intrinsic factors in the germ line as well as extrinsic factors from the surrounding somatic niche. dWnt4, in the escort cells of the adult somatic niche promotes GSC differentiation using the canonical β-cat...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Upadhyay, Maitreyi, Kuna, Michael, Tudor, Sara, Martino Cortez, Yesenia, Rangan, Prashanth
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811049/
https://ncbi.nlm.nih.gov/pubmed/29370168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007154
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