A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila

Germline stem cell (GSC) self-renewal and differentiation into gametes is regulated by both intrinsic factors in the germ line as well as extrinsic factors from the surrounding somatic niche. dWnt4, in the escort cells of the adult somatic niche promotes GSC differentiation using the canonical β-cat...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Upadhyay, Maitreyi, Kuna, Michael, Tudor, Sara, Martino Cortez, Yesenia, Rangan, Prashanth
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811049/
https://ncbi.nlm.nih.gov/pubmed/29370168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007154
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