Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

During tissue development, multipotent progenitors differentiate into specific cell types in characteristic spatial and temporal patterns. We addressed the mechanism linking progenitor identity and differentiation rate in the neural tube, where motor neuron (MN) progenitors differentiate more rapidl...

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Udgivet i:PLoS Biol
Main Authors: Sagner, Andreas, Gaber, Zachary B., Delile, Julien, Kong, Jennifer H., Rousso, David L., Pearson, Caroline A., Weicksel, Steven E., Melchionda, Manuela, Mousavy Gharavy, S. Neda, Briscoe, James, Novitch, Bennett G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811045/
https://ncbi.nlm.nih.gov/pubmed/29389974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2003127
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