Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin

The membrane-bound serine proteases prostasin and matriptase and the Kunitz-type protease inhibitors HAI-1 and HAI-2 are all expressed in human skin and may form a tightly regulated proteolysis network, contributing to skin pathophysiology. Evidence from other systems, however, suggests that the rel...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Shiao-Pieng, Kao, Chen-Yu, Chang, Shun-Cheng, Chiu, Yi-Lin, Chen, Yen-Ju, Chen, Ming-Hsing G., Chang, Chun-Chia, Lin, Yu-Wen, Chiang, Chien-Ping, Wang, Jehng-Kang, Lin, Chen-Yong, Johnson, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811018/
https://ncbi.nlm.nih.gov/pubmed/29438412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192632
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