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Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane

Matriptase and prostasin, acting as a tightly coupled proteolytic cascade, were reported to be required for epidermal barrier formation in mouse skin. Here we show that, in human skin, matriptase and prostasin are expressed with an inverse pattern over the course of differentiation. Matriptase was d...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Lai, Chih-Hsin, Chang, Shun-Cheng, Chen, Yen-Ju, Wang, Yi-Jie J., Lai, Ying-Jun J., Chang, Hsiang-Hua D., Berens, Eric B., Johnson, Michael D., Wang, Jehng-Kang, Lin, Chen-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087689/
https://ncbi.nlm.nih.gov/pubmed/27543057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.019745
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