The siRNA-mediated knockdown of GluN3A in 46C-derived neural stem cells affects mRNA expression levels of neural genes, including known iGluR interactors

For years, GluN3A was solely considered to be a dominant-negative modulator of NMDARs, since its incorporation into receptors alters hallmark features of conventional NMDARs composed of GluN1/GluN2 subunits. Only recently, increasing evidence has accumulated that GluN3A plays a more diversified role...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pachernegg, Svenja, Eilebrecht, Sebastian, Eilebrecht, Elke, Schöneborn, Hendrik, Neumann, Sebastian, Benecke, Arndt G., Hollmann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811004/
https://ncbi.nlm.nih.gov/pubmed/29438442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192242
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