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GluA2 is rapidly edited at the Q/R site during neural differentiation in vitro
The majority of AMPA receptors in the adult brain contain GluA2 subunits, which can be edited at the Q/R site, changing a glutamine to an arginine within the ion pore. Q/R editing renders AMPARs virtually Ca(2+)-impermeable, which is important for normal AMPA receptor function. Thus, all GluA2 subun...
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| Publié dans: | Front Cell Neurosci |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350408/ https://ncbi.nlm.nih.gov/pubmed/25798088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00069 |
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