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GluA2 is rapidly edited at the Q/R site during neural differentiation in vitro

The majority of AMPA receptors in the adult brain contain GluA2 subunits, which can be edited at the Q/R site, changing a glutamine to an arginine within the ion pore. Q/R editing renders AMPARs virtually Ca(2+)-impermeable, which is important for normal AMPA receptor function. Thus, all GluA2 subun...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Pachernegg, Svenja, Münster, Yvonne, Muth-Köhne, Elke, Fuhrmann, Gloria, Hollmann, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350408/
https://ncbi.nlm.nih.gov/pubmed/25798088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00069
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