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Hedgehog signaling stimulates Tenascin C to promote invasion of pancreatic ductal adenocarcinoma cells through Annexin A2

Pancreatic adenocarcinoma (PDA) is characterized by a dense desmoplastic reaction that comprises 60–90% of the tumor, while only 10–40% of the tumor is composed of malignant epithelial cells. This desmoplastic reaction is composed of stromal fibroblast cells, extracellular matrix proteins, and immun...

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Vydáno v:Cell Adh Migr
Hlavní autoři: Foley, Kelly, Muth, Stephen, Jaffee, Elizabeth, Zheng, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810754/
https://ncbi.nlm.nih.gov/pubmed/28152318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2016.1259057
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