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Hedgehog signaling stimulates Tenascin C to promote invasion of pancreatic ductal adenocarcinoma cells through Annexin A2

Pancreatic adenocarcinoma (PDA) is characterized by a dense desmoplastic reaction that comprises 60–90% of the tumor, while only 10–40% of the tumor is composed of malignant epithelial cells. This desmoplastic reaction is composed of stromal fibroblast cells, extracellular matrix proteins, and immun...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Foley, Kelly, Muth, Stephen, Jaffee, Elizabeth, Zheng, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810754/
https://ncbi.nlm.nih.gov/pubmed/28152318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2016.1259057
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