Zinc metalloproteinase ZmpC suppresses experimental pneumococcal meningitis by inhibiting bacterial invasion of central nervous systems

Streptococcus pneumoniae is a leading cause of bacterial meningitis. Here, we investigated whether pneumococcal paralogous zinc metalloproteases contribute to meningitis onset. Findings of codon-based phylogenetic analyses indicated 3 major clusters in the Zmp family; ZmpA, ZmpC, and ZmpB, with ZmpD...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Yamaguchi, Masaya, Nakata, Masanobu, Sumioka, Ryuichi, Hirose, Yujiro, Wada, Satoshi, Akeda, Yukihiro, Sumitomo, Tomoko, Kawabata, Shigetada
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810488/
https://ncbi.nlm.nih.gov/pubmed/28489958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1328333
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