Treatment of Cyclosporin A retains host defense against invasive pulmonary aspergillosis in a non-immunosuppressive murine model by preserving the myeloid cell population

Cyclosporin A (CsA) is widely used as an immunosuppressive agent for organ transplant recipients. CsA inhibits calcineurin, which is highly conserved in mammals and fungi, and thus affects both types of organism. In mammals, the immunosuppressive effect of CsA is via hampering T cell activation. In...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Wong, Sarah Sze Wah, Rasid, Orhan, Laskaris, Paris, Fekkar, Arnaud, Cavaillon, Jean-Marc, Steinbach, William J., Ibrahim-Granet, Oumaima
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810467/
https://ncbi.nlm.nih.gov/pubmed/28594271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1339007
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