Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor

Hypoxia as a result of pulmonary tissue damage due to unresolved inflammation during invasive pulmonary aspergillosis (IPA) is associated with a poor outcome. Aspergillus fumigatus can exploit the hypoxic microenvironment in the lung, but the inflammatory response required for fungal clearance can b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gresnigt, Mark S., Rekiki, Abdessalem, Rasid, Orhan, Savers, Amélie, Jouvion, Grégory, Dannaoui, Eric, Parlato, Marianna, Fitting, Catherine, Brock, Matthias, Cavaillon, Jean-Marc, van de Veerdonk, Frank L., Ibrahim-Granet, Oumaïma
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877709/
https://ncbi.nlm.nih.gov/pubmed/27215684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26490
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