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HMGB1 bound to cisplatin–DNA adducts undergoes extensive acetylation and phosphorylation in vivo
Cisplatin, one of the most effective anticancer drugs, is a DNA-damaging agent that induces cell death primarily by apoptosis. For many years, HMGB1 has been known to be a recognition protein for cisplatin–DNA lesions. Here, an application of a biomolecular probe based on a peptide–oligonucleotide c...
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| Publicat a: | Chem Sci |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5810237/ https://ncbi.nlm.nih.gov/pubmed/29449921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc03650f |
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