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Honokiol suppresses proliferation and induces apoptosis via regulation of the miR-21/PTEN/PI3K/AKT signaling pathway in human osteosarcoma cells

Honokiol (HNK) is a small biphenolic compound, which exerts antineoplastic effects in various types of cancer. However, the mechanism underlying the antitumor effects of HNK in osteosarcoma (OS) cells is not yet fully understood. Emerging evidence has indicated that microRNAs (miRNAs/miRs) serve key...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Yang, Jiexiang, Zou, Yonggen, Jiang, Dianmin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810212/
https://ncbi.nlm.nih.gov/pubmed/29393336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3433
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