ROS responsive resveratrol delivery from LDLR peptide conjugated PLA-coated mesoporous silica nanoparticles across the blood–brain barrier

BACKGROUND: Oxidative stress acts as a trigger in the course of neurodegenerative diseases and neural injuries. An antioxidant-based therapy can be effective to ameliorate the deleterious effects of oxidative stress. Resveratrol (RSV) has been shown to be effective at removing excess reactive oxygen...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Nanobiotechnology
Auteurs principaux: Shen, Yang, Cao, Bin, Snyder, Noah R., Woeppel, Kevin M., Eles, James R., Cui, Xinyan Tracy
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810018/
https://ncbi.nlm.nih.gov/pubmed/29433522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0340-7
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