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Herpes Simplex Virus 1 DNA Polymerase RNase H Activity Acts in a 3′-to-5′ Direction and Is Dependent on the 3′-to-5′ Exonuclease Active Site

The catalytic subunit (Pol) of herpes simplex virus 1 (HSV-1) DNA polymerase has been extensively studied both as a model for other family B DNA polymerases and for its differences from these enzymes as an antiviral target. Among the activities of HSV-1 Pol is an intrinsic RNase H activity that clea...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Lawler, Jessica L., Mukherjee, Purba, Coen, Donald M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809741/
https://ncbi.nlm.nih.gov/pubmed/29237844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01813-17
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