Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication

Human parvovirus B19 (B19V) infection of human erythroid progenitor cells (EPCs) induces a DNA damage response and cell cycle arrest at late S phase, which facilitates viral DNA replication. However, it is not clear exactly which cellular factors are employed by this single-stranded DNA virus. Here,...

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Veröffentlicht in:J Virol
Hauptverfasser: Zou, Wei, Wang, Zekun, Xiong, Min, Chen, Aaron Yun, Xu, Peng, Ganaie, Safder S., Badawi, Yomna, Kleiboeker, Steve, Nishimune, Hiroshi, Ye, Shui Qing, Qiu, Jianming
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809726/
https://ncbi.nlm.nih.gov/pubmed/29237843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01881-17
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