Early Actions of Anti–Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Drugs on Angiogenic Blood Vessels

Tumors induce their heterogeneous vasculature by secreting vascular endothelial growth factor (VEGF)-A. Anti-VEGF/VEGF receptor (VEGFR) drugs treat cancer, but the underlying mechanisms remain unclear. An adenovirus expressing VEGF-A (Ad-VEGF-A(164)) replicates the tumor vasculature in mice without...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Sitohy, Basel, Chang, Sunghee, Sciuto, Tracey E., Masse, Elizabeth, Shen, Mei, Kang, Peter M., Jaminet, Shou-Ching, Benjamin, Laura E., Bhatt, Rupal S., Dvorak, Ann M., Nagy, Janice A., Dvorak, Harold F.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809587/
https://ncbi.nlm.nih.gov/pubmed/28736316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.06.010
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires