Leucine-Rich Repeat Kinase 2 Controls the Ca(2+)/Nuclear Factor of Activated T Cells/IL-2 Pathway during Aspergillus Non-Canonical Autophagy in Dendritic Cells

The Parkinson’s disease-associated protein, Leucine-rich repeat kinase 2 (LRRK2), a known negative regulator of nuclear factor of activated T cells (NFAT), is expressed in myeloid cells such as macrophages and dendritic cells (DCs) and is involved in the host immune response against pathogens. Since...

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Detalhes bibliográficos
Publicado no:Front Immunol
Principais autores: Wong, Alicia Yoke Wei, Oikonomou, Vasilis, Paolicelli, Giuseppe, De Luca, Antonella, Pariano, Marilena, Fric, Jan, Tay, Hock Soon, Ricciardi-Castagnoli, Paola, Zelante, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809498/
https://ncbi.nlm.nih.gov/pubmed/29472933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00210
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