Aspergillus fumigatus tryptophan metabolic route differently affects host immunity

Indoleamine 2,3-dioxygenases (IDOs) degrade l-tryptophan to kynurenines and drive the de novo synthesis of nicotinamide adenine dinucleotide. Unsurprisingly, various invertebrates, vertebrates, and even fungi produce IDO. In mammals, IDO1 also serves as a homeostatic regulator, modulating immune res...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Zelante, Teresa, Choera, Tsokyi, Beauvais, Anne, Fallarino, Francesca, Paolicelli, Giuseppe, Pieraccini, Giuseppe, Pieroni, Marco, Galosi, Claudia, Beato, Claudia, De Luca, Antonella, Boscaro, Francesca, Romoli, Riccardo, Liu, Xin, Warris, Adilia, Verweij, Paul E., Ballard, Eloise, Borghi, Monica, Pariano, Marilena, Costantino, Gabriele, Calvitti, Mario, Vacca, Carmine, Oikonomou, Vasilis, Gargaro, Marco, Wong, Alicia Yoke Wei, Boon, Louis, den Hartog, Marcel, Spáčil, Zdeněk, Puccetti, Paolo, Latgè, Jean-Paul, Keller, Nancy P., Romani, Luigina
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844877/
https://ncbi.nlm.nih.gov/pubmed/33503414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108673
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