Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system

Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that transform...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Saito, Yoshimasa, Nakaoka, Toshiaki, Muramatsu, Toshihide, Ojima, Hidenori, Sukeda, Aoi, Sugiyama, Yuko, Uchida, Ryoei, Furukawa, Ryo, Kitahara, Aya, Sato, Toshiro, Kanai, Yae, Saito, Hidetsugu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809480/
https://ncbi.nlm.nih.gov/pubmed/29434290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21121-6
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