Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system

Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that transform...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saito, Yoshimasa, Nakaoka, Toshiaki, Muramatsu, Toshihide, Ojima, Hidenori, Sukeda, Aoi, Sugiyama, Yuko, Uchida, Ryoei, Furukawa, Ryo, Kitahara, Aya, Sato, Toshiro, Kanai, Yae, Saito, Hidetsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809480/
https://ncbi.nlm.nih.gov/pubmed/29434290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21121-6
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