The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy

Diabetic retinopathy (DR) is a retinal microvascular disease characterized by inflammatory and angiogenic pathways. In this study, we evaluated NLRP3 inflammasome in a double transgenic mouse model, Akimba (Ins2(Akita)xVEGF(+/−)), which demonstrates hyperglycemia, vascular hyperpermeability and neov...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Chaurasia, Shyam S., Lim, Rayne R., Parikh, Bhav H., Wey, Yeo Sia, Tun, Bo Bo, Wong, Tien Yin, Luu, Chi D., Agrawal, Rupesh, Ghosh, Arkasubhra, Mortellaro, Alessandra, Rackoczy, Elizabeth, Mohan, Rajiv R., Barathi, Veluchamy A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809448/
https://ncbi.nlm.nih.gov/pubmed/29434227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21198-z
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