The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy

Diabetic retinopathy (DR) is a retinal microvascular disease characterized by inflammatory and angiogenic pathways. In this study, we evaluated NLRP3 inflammasome in a double transgenic mouse model, Akimba (Ins2(Akita)xVEGF(+/−)), which demonstrates hyperglycemia, vascular hyperpermeability and neov...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chaurasia, Shyam S., Lim, Rayne R., Parikh, Bhav H., Wey, Yeo Sia, Tun, Bo Bo, Wong, Tien Yin, Luu, Chi D., Agrawal, Rupesh, Ghosh, Arkasubhra, Mortellaro, Alessandra, Rackoczy, Elizabeth, Mohan, Rajiv R., Barathi, Veluchamy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809448/
https://ncbi.nlm.nih.gov/pubmed/29434227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21198-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados