Impaired Control of Epstein–Barr Virus Infection in B-Cell Expansion with NF-κB and T-Cell Anergy Disease

B-cell expansion with NF-κB and T-cell anergy (BENTA) disease is a B-cell-specific lymphoproliferative disorder caused by germline gain-of-function mutations in CARD11. These mutations force the CARD11 scaffold into an open conformation capable of stimulating constitutive NF-κB activation in lymphoc...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Arjunaraja, Swadhinya, Angelus, Pamela, Su, Helen C., Snow, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809398/
https://ncbi.nlm.nih.gov/pubmed/29472930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00198
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