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Intrinsic Plasma Cell Differentiation Defects in B Cell Expansion with NF-κB and T Cell Anergy Patient B Cells

B cell Expansion with NF-κB and T cell Anergy (BENTA) disease is a novel B cell lymphoproliferative disorder caused by germline, gain-of-function mutations in the lymphocyte scaffolding protein CARD11, which drives constitutive NF-κB signaling. Despite dramatic polyclonal expansion of naive and imma...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Immunol
Main Authors: Arjunaraja, Swadhinya, Nosé, Brent D., Sukumar, Gauthaman, Lott, Nathaniel M., Dalgard, Clifton L., Snow, Andrew L.
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539167/
https://ncbi.nlm.nih.gov/pubmed/28824638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00913
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