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Adenosine A(2a) Receptor Blockade Diminishes Wnt/β-Catenin Signaling in a Murine Model of Bleomycin-Induced Dermal Fibrosis

Adenosine A(2a) receptor (A(2a)R) stimulation promotes the synthesis of collagens I and III, and we have recently demonstrated that there is crosstalk between the A(2a)R and WNT/β-catenin signaling pathway. In in vitro studies, A(2a)R signaling for collagen III expression was mediated by WNT/β-caten...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Zhang, Jin, Corciulo, Carmen, Liu, Hailing, Wilder, Tuere, Ito, Mayumi, Cronstein, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809334/
https://ncbi.nlm.nih.gov/pubmed/28667836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.05.005
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