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Mature hippocampal neurons require LIS1 for synaptic integrity: implications for cognition

BACKGROUND: LIS1 (aka PAFAH1B1), a critical mediator of neuronal migration in developing brain, is expressed throughout life. However, relatively little is known about LIS1 function in the mature brain. We previously demonstrated LIS1 involvement in the formation and turnover of synaptic protrusions...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Sudarov, Anamaria, Zhang, Xin-Jun, Braunstein, Leighton, Castro, Eve Lo, Singh, Shawn, Taniguchi, Yu, Raj, Ashish, Shi, Song-Hai, Moore, Holly, Ross, M. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809292/
https://ncbi.nlm.nih.gov/pubmed/29150182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.09.011
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