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Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability

Integrin binding to bioengineered hydrogel scaffolds is essential for tissue regrowth and regeneration, yet not all integrin binding can lead to tissue repair. Here, we show that through engineering hydrogel materials to promote α3/α5β1 integrin binding, we can promote the formation of a space filli...

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Bibliografische gegevens
Gepubliceerd in:Nat Mater
Hoofdauteurs: Li, Shuoran, Nih, Lina R., Bachman, Haylee, Fei, Peng, Li, Yilei, Nam, Eunwoo, Dimatteo, Robert, Carmichael, S. Thomas, Barker, Thomas H., Segura, Tatiana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809173/
https://ncbi.nlm.nih.gov/pubmed/28783156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4954
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