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Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability

Integrin binding to bioengineered hydrogel scaffolds is essential for tissue regrowth and regeneration, yet not all integrin binding can lead to tissue repair. Here, we show that through engineering hydrogel materials to promote α3/α5β1 integrin binding, we can promote the formation of a space filli...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Li, Shuoran, Nih, Lina R., Bachman, Haylee, Fei, Peng, Li, Yilei, Nam, Eunwoo, Dimatteo, Robert, Carmichael, S. Thomas, Barker, Thomas H., Segura, Tatiana
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809173/
https://ncbi.nlm.nih.gov/pubmed/28783156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4954
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