Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility

Decreased contractility in the non-ischemic border zone surrounding a MI is in part due to degradation of cardiomyocyte sarcomeric components by intracellular matrix metalloproteinase-2 (MMP-2). We recently reported that MMP-2 levels were increased in the border zone after a MI and that treatment wi...

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Publicat a:PLoS One
Autors principals: Spaulding, Kimberly, Takaba, Kiyoaki, Collins, Alexander, Faraji, Farshid, Wang, Guanying, Aguayo, Esteban, Ge, Liang, Saloner, David, Wallace, Arthur W., Baker, Anthony J., Lovett, David H., Ratcliffe, Mark B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809072/
https://ncbi.nlm.nih.gov/pubmed/29432443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192720
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