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Single cell on-chip whole genome amplification via micropillar arrays for reduced amplification bias
Single cell whole genome amplification is susceptible to amplification biases that impact the accuracy of single cell sequencing data. To address this, we have developed a microfluidic device for the isolation and purification of genomic DNA from individual cells. The device uses a micropillar array...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5809021/ https://ncbi.nlm.nih.gov/pubmed/29432426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191520 |
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