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Illumina Library Preparation for Sequencing the GC-Rich Fraction of Heterogeneous Genomic DNA
Standard Illumina libraries are biased toward sequences of intermediate GC-content. This results in an underrepresentation of GC-rich regions in sequencing projects of genomes with heterogeneous base composition, such as mammals and birds. We developed a simple, cost-effective protocol to enrich she...
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| Publicado en: | Genome Biol Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808798/ https://ncbi.nlm.nih.gov/pubmed/29385572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evy022 |
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