A role for bacterial urease in gut dysbiosis and Crohn’s disease

Gut dysbiosis during inflammatory bowel disease involves alterations in the gut microbiota associated with inflammation of the host gut. We used a combination of shotgun metagenomic sequencing and metabolomics to analyze fecal samples from pediatric patients with Crohn’s disease and found an associa...

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Udgivet i:Sci Transl Med
Main Authors: Ni, Josephine, Shen, Ting-Chin David, Chen, Eric Z., Bittinger, Kyle, Bailey, Aubrey, Roggiani, Manuela, Sirota-Madi, Alexandra, Friedman, Elliot S., Chau, Lillian, Lin, Andrew, Nissim, Ilana, Scott, Justin, Lauder, Abigail, Hoffmann, Christian, Rivas, Gloriany, Albenberg, Lindsey, Baldassano, Robert N., Braun, Jonathan, Xavier, Ramnik J., Clish, Clary B., Yudkoff, Marc, Li, Hongzhe, Goulian, Mark, Bushman, Frederic D., Lewis, James D., Wu, Gary D.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808452/
https://ncbi.nlm.nih.gov/pubmed/29141885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aah6888
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