Engineering the gut microbiota to treat hyperammonemia

Increasing evidence indicates that the gut microbiota can be altered to ameliorate or prevent disease states, and engineering the gut microbiota to therapeutically modulate host metabolism is an emerging goal of microbiome research. In the intestine, bacterial urease converts host-derived urea to am...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Shen, Ting-Chin David, Albenberg, Lindsey, Bittinger, Kyle, Chehoud, Christel, Chen, Ying-Yu, Judge, Colleen A., Chau, Lillian, Ni, Josephine, Sheng, Michael, Lin, Andrew, Wilkins, Benjamin J., Buza, Elizabeth L., Lewis, James D., Daikhin, Yevgeny, Nissim, Ilana, Yudkoff, Marc, Bushman, Frederic D., Wu, Gary D.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563680/
https://ncbi.nlm.nih.gov/pubmed/26098218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79214
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