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Engineering the gut microbiota to treat hyperammonemia

Increasing evidence indicates that the gut microbiota can be altered to ameliorate or prevent disease states, and engineering the gut microbiota to therapeutically modulate host metabolism is an emerging goal of microbiome research. In the intestine, bacterial urease converts host-derived urea to am...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Shen, Ting-Chin David, Albenberg, Lindsey, Bittinger, Kyle, Chehoud, Christel, Chen, Ying-Yu, Judge, Colleen A., Chau, Lillian, Ni, Josephine, Sheng, Michael, Lin, Andrew, Wilkins, Benjamin J., Buza, Elizabeth L., Lewis, James D., Daikhin, Yevgeny, Nissim, Ilana, Yudkoff, Marc, Bushman, Frederic D., Wu, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563680/
https://ncbi.nlm.nih.gov/pubmed/26098218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79214
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