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A novel eight amino acid insertion contributes to the hemagglutinin cleavability and the virulence of a highly pathogenic avian influenza A (H7N3) virus in mice

In 2012, an avian influenza A H7N3 (A/Mexico/InDRE7218/2012; Mx/7218) virus was responsible for two confirmed cases of human infection and led to the death or culling of more than 22 million chickens in Jalisco, Mexico. Interestingly, this virus acquired an 8-amino acid (aa)-insertion (..PENPK-DRKSR...

詳細記述

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書誌詳細
出版年:Virology
主要な著者: Sun, Xiangjie, Belser, Jessica A., Tumpey, Terrence M.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808403/
https://ncbi.nlm.nih.gov/pubmed/26629952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.10.032
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