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Additive Dose Response Models: Explicit Formulation and the Loewe Additivity Consistency Condition
High-throughput techniques allow for massive screening of drug combinations. To find combinations that exhibit an interaction effect, one filters for promising compound combinations by comparing to a response without interaction. A common principle for no interaction is Loewe Additivity which is bas...
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| Publicado en: | Front Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808155/ https://ncbi.nlm.nih.gov/pubmed/29467650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00031 |
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