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Tissue Factor Regulation by miR-520g in Primitive Neuronal Brain Tumor Cells: A Possible Link between Oncomirs and the Vascular Tumor Microenvironment

Pediatric embryonal brain tumors with multilayered rosettes demonstrate a unique oncogenic amplification of the chromosome 19 miRNA cluster, C19MC. Because oncogenic lesions often cause deregulation of vascular effectors, including procoagulant tissue factor (TF), this study explores whether there i...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: D'Asti, Esterina, Huang, Annie, Kool, Marcel, Meehan, Brian, Chan, Jennifer A., Jabado, Nada, Korshunov, Andrey, Pfister, Stefan M., Rak, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808154/
https://ncbi.nlm.nih.gov/pubmed/26687818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.10.020
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