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No major role of norepinephrine transporter gene variations in the cardiostimulant effects of MDMA

PURPOSE: Methylenedioxymethamphetamine (MDMA, ecstasy) is used recreationally and frequently leads to sympathomimetic toxicity. MDMA produces cardiovascular and subjective stimulant effects that were shown to partially depend on the norepinephrine transporter (NET)-mediated release of norepinephrine...

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Détails bibliographiques
Publié dans:Eur J Clin Pharmacol
Auteurs principaux: Vizeli, Patrick, Meyer zu Schwabedissen, Henriette E., Liechti, Matthias E.
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808057/
https://ncbi.nlm.nih.gov/pubmed/29198060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-017-2392-2
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