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The IAP family member BRUCE regulates autophagosome–lysosome fusion
Autophagy has an important role in cellular homeostasis by degrading and recycling cytotoxic components. Ubiquitination is known to target cargoes for autophagy; however, key components of this pathway remain elusive. Here we performed an RNAi screen to uncover ubiquitin modifiers that are required...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5807552/ https://ncbi.nlm.nih.gov/pubmed/29426817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02823-x |
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