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Verification of radiodynamic therapy by medical linear accelerator using a mouse melanoma tumor model

Combined treatment with 5-aminolevulinic acid (5-ALA) and X-rays improves tumor suppression in vivo. This is because the accumulated protoporphyrin IX from 5-ALA enhances the generation of ROS by the X-ray irradiation. In the present study, a high-energy medical linear accelerator was used instead o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takahashi, Junko, Murakami, Mami, Mori, Takashi, Iwahashi, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807383/
https://ncbi.nlm.nih.gov/pubmed/29426920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21152-z
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