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Estimating dose-specific cell division and apoptosis rates from chemo-sensitivity experiments

In-vitro chemo-sensitivity experiments are an essential step in the early stages of cancer therapy development, but existing data analysis methods suffer from problems with fitting, do not permit assessment of uncertainty, and can give misleading estimates of cell growth inhibition. We present an ap...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Liu, Yiyi, Crawford, Forrest W.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807362/
https://ncbi.nlm.nih.gov/pubmed/29426887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21017-5
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