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Estimating dose-specific cell division and apoptosis rates from chemo-sensitivity experiments

In-vitro chemo-sensitivity experiments are an essential step in the early stages of cancer therapy development, but existing data analysis methods suffer from problems with fitting, do not permit assessment of uncertainty, and can give misleading estimates of cell growth inhibition. We present an ap...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Liu, Yiyi, Crawford, Forrest W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807362/
https://ncbi.nlm.nih.gov/pubmed/29426887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21017-5
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