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Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and typically fatal lung disease with a very low survival rate. Excess accumulation of fibroblasts, myofibroblasts and extracellular matrix creates hypoxic conditions within the lungs, causing asphyxiation. Hypoxia is, therefore, one of t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Senavirathna, Lakmini Kumari, Huang, Chaoqun, Yang, Xiaoyun, Munteanu, Maria Cristina, Sathiaseelan, Roshini, Xu, Dao, Henke, Craig A., Liu, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807313/
https://ncbi.nlm.nih.gov/pubmed/29426911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21073-x
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