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Hypoxia and transforming growth factor β1 regulation of long non‐coding RNA transcriptomes in human pulmonary fibroblasts

One of the key characteristics of idiopathic pulmonary fibrosis (IPF) is accumulation of excess fibrous tissue in the lung, which leads to hypoxic conditions. Transforming growth factor (TGF) β is a major mediator that promotes the differentiation of fibroblasts to myofibroblasts. However, how hypox...

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Pubblicato in:Physiol Rep
Autori principali: Senavirathna, Lakmini K., Huang, Chaoqun, Pushparaj, Samuel, Xu, Dao, Liu, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954122/
https://ncbi.nlm.nih.gov/pubmed/31925944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14343
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