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Ablating both Fabp1 and Scp2/Scpx (TKO) Induces Hepatic Phospholipid and Cholesterol Accumulation in High Fat-fed Mice
Although singly ablating Fabp1 or Scp2/Scpx genes may exacerbate the impact of high fat diet (HFD) on whole body phenotype and non-alcoholic fatty liver disease (NAFLD), concomitant upregulation of the non-ablated gene, preference for ad libitum fed HFD, and sex differences complicate interpretation...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5807141/ https://ncbi.nlm.nih.gov/pubmed/29307784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2017.12.013 |
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