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Robo1 Forms a Compact Dimer-of-Dimers Assembly
Roundabout (Robo) receptors provide an essential repulsive cue in neuronal development following Slit ligand binding. This important signaling pathway can also be hijacked in numerous cancers, making Slit-Robo an attractive therapeutic target. However, little is known about how Slit binding mediates...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5807052/ https://ncbi.nlm.nih.gov/pubmed/29307485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.12.003 |
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