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Robo1 Forms a Compact Dimer-of-Dimers Assembly
Roundabout (Robo) receptors provide an essential repulsive cue in neuronal development following Slit ligand binding. This important signaling pathway can also be hijacked in numerous cancers, making Slit-Robo an attractive therapeutic target. However, little is known about how Slit binding mediates...
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| Publicat a: | Structure |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5807052/ https://ncbi.nlm.nih.gov/pubmed/29307485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.12.003 |
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