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SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains

The SOXE transcription factors SOX8, SOX9 and SOX10 are master regulators of mammalian development directing sex determination, gliogenesis, pancreas specification and neural crest development. We identified a set of palindromic SOX binding sites specifically enriched in regulatory regions of melano...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Yong-Heng, Jankowski, Aleksander, Cheah, Kathryn S. E., Prabhakar, Shyam, Jauch, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445065/
https://ncbi.nlm.nih.gov/pubmed/26013289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10398
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